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Sulfonylurea derivatives are a class of drugs that are used in the management of type 2 diabetes. Type 2 diabetes is characterized by resistance to insulin. These drugs work by increasing the production of insulin in the pancreas. Use of drugs of this category is contraindicated in various situations such as allergy to sulfa-based drugs and advanced liver or kidney disease. Another important class of medication for managing type 2 diabetes is called biguanides. Drugs of this class inhibit the production of sugar in the liver and can cause the loss of weight. If properly administered, biguanides not only help to reduce fasting blood sugar levels but also are also beneficial in reducing LDL cholesterol, triglycerides and can aid in weight loss. We notice that various anti-diabetic medications except for insulin, work in a variety of ways to keep the blood sugar levels within limits. Another example of anti diabetic drugs for type 2 diabetic patients is the drugs known as Thiazolidinediones or glitazones, increase the efficiency of the hormone insulin and thus result in bringing the blood sugar level down. Certain medications promote the secretion of insulin immediately after a meal, in response to the likely rise in the level of blood sugar. These drugs known as Meglitinides are quicker acting than other diabetic medications. Related Articles |